Authors: Adwait Oka, Meghna Talekar, Qijun Ouyang, Ed Luther, Mansoor Amiji

Journal: Journal of Clinical & Cellular Immunology (2015)

Institution: Northeastern university

Research Areas: Cancer research, Immunology

Cell Lines: J774A, 1, SKOV3 (MJ774A.1 murine macrophage cell line; SKOV3 human ovarian cancer cells)

Summary: Holographic assessment using Holomonitor M4 of the co-cultured cells in real-time showed differences in motility and morphology of macrophages with mir-155 ME treated cells showing greater cellular interaction between the two phenotypes.

Keywords: Holomonitor M4, cell Morphology, cell motility, tumor-associated macrophages, Macrophage polarization, MicroRNA-155, Water-in-oil-in-water multiple emulsions