Authors: Dr. Alexey N. Butkevich, Dr. Vladimir N. Belov, Dr. Kirill Kolmakov, Dr. Viktor V. Sokolov, Dr. Heydar Shojaei, Dr. Sven C. Sidenstein, Dr. Dirk Kamin, Jessica Matthias, Dr. Rifka Vlijm, Dr. Johann Engelhardt, Prof. Dr. Dr. Stefan W. Hell

Journal: Chemistry — A European Journal (2017)

Institution: Max Planck Institute for Biophysical Chemistry

Research Areas: Method development

Cell Lines: Drosophilia S2 cells

Summary: Cell viability in the presence of dyes in the centromeres was verified by measuring cell morphology of Drosophila S2 cells using a holographic microscope (Holomonitor M4). images and measures cells without using invasive dyes or reagents. Using HoloMonitor, the authors proved that cells stay alive and continue to divide after staining them with the improved super-resolution dyes.

Keywords: HoloMonitor M4, Cell quality, Cell morphology, Cell proliferation