Peer-reviewed Publications

Below you will find summaries and links to peer-reviewed publications and book chapters discussing HoloMonitor, its applications and the core technology — digital holographic and quantitative phase imaging (QPI) microscopy.

Evaluation of the Toxicity on Lung Cells of By-Products Present in Naphthalene Secondary Organic Aerosols

Authors: Yuri Lima de Albuquerque et al.

Journal: Life (2021)

Research Areas: Toxicology

Cell Lines: A549

Keywords: HoloMonitor M4, cell morphology, cell movements, PAHs, secondary organic aerosols, RTCA, naphthoquinone

Epac1 signaling pathway mediates the damage and apoptosis of inner ear hair cells after noise exposure in a rat model

Authors: Fanfan Sun et al.

Journal: Neuroscience (2021)

Research Areas: Neuscience

Cell Lines: HEI-OC1

Keywords: HoloMonitor M4, cell proliferation, EpacCaMKII, noise-induced hearing loss (NIHL), apoptosis, Hearing loss studies

Targeted Delivery of Combination Therapeutics Using Monoclonal Antibody 2C5-Modified Immunoliposomes for Cancer Therapy

Authors: Radhika Narayanaswamy et al.

Journal: Pharmaceutical Research (2021)

Research Areas: Drug research

Cell Lines: MDA-MD-231

Keywords: HoloMonitor M4, cell Proliferation and cell Morphology, cancer therapy

Cytoplasmic localization of prostate-specific membrane antigen inhibitors may confer advantages for targeted cancer therapies

Authors: essica Matthias et al.

Journal: Cancer Research (2021)

Research Areas: Cytotoxicity

Cell Lines: LNCaP and 22Rv1

Keywords: HoloMonitor M4, Cell Proliferation

A novel ROCK inhibitor: off-target effects of metformin

Authors: Aysun Özdemir et al.

Journal: Turkish Journal of Biology (2021)

Research Areas: Drug research

Cell Lines: HeLa and MCF-7

Keywords: HoloMonitor M4, cell morphology, connectivity MAP, Rho kinase, metformin, off-target effect, oral antidiabetics

Monobutyl phthalate can induce autophagy and metabolic disorders by activating the ire1a-xbp1 pathway in zebrafish liver

Authors: Ying Zhang et al.

Journal: Journal of Hazardous Materials (2021)

Research Areas: Toxicology

Cell Lines: Zebra fish (AB strain) liver cells

Keywords: HoloMonitor M4, cell morphology, ER stress, UPR pathway, Autophagy, Glucose metabolism, Lipid metabolism, Chemical toxicity

Snail Overexpression Alters the microRNA Content of Extracellular Vesicles Released from HT29 Colorectal Cancer Cells and Activates Pro-Inflammatory State In Vivo

Authors: Izabela Papiewska-Pająk et al.

Journal: Cancers (2021)

Research Areas: Cancer research

Cell Lines: HT-29

Keywords: HoloMonitor M4, cell motility, snail transcription factor, extracellular vesicles, colon cancer, pre-metastatic niche

Cellular Effects of Cystatins

Authors: Hunaiti et al.

Research Areas: Cancer research

Keywords: Doctoral thesis, cancer and oncology, cystatin c, cystatin d, galectin-1, puncta assay, holomonitor, cancer cells, apoptosis, cathepsin c

Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps

Authors: Livia P. Mendes et al.

Journal: mAbs (2020)

Research Areas: Cell Research

Cell Lines: HL-60

Keywords: HoloMonitor M4, cell morphology, neutrophil extracellular traps, monoclonal antibody, active targeting2C5, microfluidic study

Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer

Authors: Julius Semenas et al.

Journal: Molecular Oncology (2020)

Research Areas: Cancer research

Cell Lines: PC-3

Keywords: HoloMonitor M4, Cell morphology, castration-resistant prostate cancer, estrogen receptor, PI3K/AKT pathway andtamoxifen, PIP5K1a, targeted therapy

Efficient and crucial quality control of HAP1 cell ploidy status

Authors: Tobias B. Beigl et al.

Journal: Biology Open (2020)

Research Areas: Cell Research

Cell Lines: HAP1

Keywords: HoloMonitor M4, Single cell tracking, Cell morphology and cell movements, HAP1, Near-haploid human cell line, CRISPR/Cas9, Gene editing, Clustered palindromic repeats, Cas9 enzyme, Cell phenotype analyses, Microscopy genetic disease cell model, Cell culture quality control

Smart drug combinations for cervical cancer: dual targeting of Bcl-2 family of proteins and aurora kinases

Authors: Jacklyn Yumol et al.

Journal: Am J Cancer Res (2020)

Research Areas: Cancer research

Cell Lines: HeLa

Keywords: HoloMonitor M4, cell morphology, HPV, aurora kinase, cervical cancer, alisertib

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