Advancing Cancer Research with Quantitative Live Cell Imaging
Cancer is a leading human disease with persistently high mortality rates. Thus, understanding the how, where, why and with whom metastatic cancer cells disseminate and proliferate is one of the highest importance in cancer research. The HoloMonitor live cell imaging system advances your cancer research with a non-invasive way to measure and quantify cell activity in real-time without compromising the integrity of your precious cells. Therefore, you can get more accurate and native results from your experiments.
A live cell analysis tool with real-time data
Find out more about how HoloMonitor live cell imaging can accelerate your cancer research!
Featured publications within cancer research
Measure mitotic activity in melanocytes
Cutaneous melanoma is deadly skin cancer. The activating mutation BARFV600E mutation exists both in moles and over half cutaneous melanomas.
In this study, in order to investigate why the same mutation has such different consequences in moles and melanomas, the authors using HoloMonitor studied cell proliferation, cell dry mass, cell death and cell growth rate. The experiments showed by increasing the levels of two microRNAs in melanocytes induces mitotic failure, genome duplication, and proliferation arrest. BRAFV600E induces a similar proliferation arrest in primary human melanocytes that is both reversible and conditional depending on the differentiation state of the melanocyte.
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The secrets to truly controlled cell experiments for cancer research
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Answer cancer research questions with quantitative live cell imaging
Browsing publications in cancer research
Get inspired by other research fellows, and learn how HoloMonitor quantitative live cell imaging can benefit your cancer research:
Evaluation of Holographic Imaging Cytometer HoloMonitor M4 Motility Applications
Journal: Cytometry Part A (2018)
Research Areas: Cancer research
Cell Lines: 1205Lu and WM793
Comparative cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids
Journal: Beilstein Journal of Organic Chemistry (2018)
Research Areas: Cancer research
Cell Lines: A2058
Cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids
Journal: Beilstein J. Org. Chem. (2018)
Research Areas: Cancer Research
Cell Lines: A2058
Ulleungdin, a lasso peptide with cancer cell migration inhibitory activity discovered by the genome mining approach
Journal: J. Nat. Prod. (2018)
Research Areas: Cancer Research
Cell Lines: A549
TRPM2 Modulates Neutrophil Attraction to Murine Tumor Cells by Regulating CXCL2 Expression
Journal: Cancer Immunology, Immunotherapy (2018)
Research Areas: Cancer research
Cell Lines: 4Ti, AT3, TRPM2, LLC, human neutrophils
Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
Journal: Cancer Cell (2018)
Research Areas: Cancer research
Cell Lines: Melanocytes